Development and characterisation of ibuprofen-loaded nanoemulsion with enhanced oral bioavailability
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چکیده
منابع مشابه
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15 صفحه اولBioavailability of ibuprofen following oral administration of standard ibuprofen, sodium ibuprofen or ibuprofen acid incorporating poloxamer in healthy volunteers
BACKGROUND The aim of this study was to compare the pharmacokinetic properties of sodium ibuprofen and ibuprofen acid incorporating poloxamer with standard ibuprofen acid tablets. METHODS Twenty-two healthy volunteers were enrolled into this randomised, single-dose, 3-way crossover, open-label, single-centre, pharmacokinetic study. After 14 hours' fasting, participants received a single dose ...
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ژورنال
عنوان ژورنال: Heliyon
سال: 2020
ISSN: 2405-8440
DOI: 10.1016/j.heliyon.2020.e04570